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TAL1 complex in human T-cell acute lymphoblastic leukemia (RPMI-8402)

ABSTRACT: The oncogenic transcription factor TAL1/SCL is aberrantly overexpressed in over 40% of cases of T-cell acute lymphoblastic leukemia (T-ALL), emphasizing the importance of the TAL1-regulated transcriptional program in the molecular pathogenesis of T-ALL. Here we identify regions occupied by TAL1 and its regulatory partners HEB, E2A, and GATA3 in a T-ALL cell line (RPMI-8402).

ORGANISM(S): Homo sapiens

PROVIDER: GSE39179 | GEO | 2012/07/09

SECONDARY ACCESSION(S): PRJNA170151

REPOSITORIES: GEO

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