Dataset Information


Comparative transcriptomics of Atlantic Salmo salar, chum Onchorhynchus keta and pink salmon O. gorbuscha responding to salmon lice Lepeophtheirus salmonis infections

ABSTRACT: The present work characterizes the response of co-habited Atlantic (Salmo salar), chum (Oncorhynchus keta) and pink salmon (Oncorhynchus gorbuscha) to sea lice infections. Atlantic and pink salmon anterior kidney samples were profiled at three time points over nine days after the start of an experimental infection. Chum salmon anterior kidney was profiled at day six post infection only. All three species were also profiled at six days post exposure for skin responses of the pectoral fin, typically associated with lice infection. Overall design: Anterior kidney was profiled at day 3, 6, 9 post exposure to lice infection in Atlantic and pink salmon, but only at 6 days post exposure in chum salmon (for each day/species n = 10 for control, 10 for infected). Controls were treated exactly as experimental, but with the addition of seawater only (no lice). Time-matched controls were used for analysis. Please note that each tissue/species combination was normalized separately and then indirectly compared.

INSTRUMENT(S): Agilent-025055 Koop Lab Salmonid 44k


PROVIDER: GSE48337 | GEO | 2014-02-24



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Comparative transcriptomics of Atlantic Salmo salar, chum Oncorhynchus keta and pink salmon O. gorbuscha during infections with salmon lice Lepeophtheirus salmonis.

Sutherland Ben J G BJ   Koczka Kim W KW   Yasuike Motoshige M   Jantzen Stuart G SG   Yazawa Ryosuke R   Koop Ben F BF   Jones Simon R M SR  

BMC genomics 20140315

BACKGROUND: Salmon species vary in susceptibility to infections with the salmon louse (Lepeophtheirus salmonis). Comparing mechanisms underlying responses in susceptible and resistant species is important for estimating impacts of infections on wild salmon, selective breeding of farmed salmon, and expanding our knowledge of fish immune responses to ectoparasites. Herein we report three L. salmonis experimental infection trials of co-habited Atlantic Salmo salar, chum Oncorhynchus keta and pink s  ...[more]

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