Dataset Information


DNA methylation Landscape of body size variation in sheep

ABSTRACT: Examination the DNA methylation statues of the main subpopulation of Chinese Mongolian sheep. A high quality methylome of Chinese Mongolian sheep was obtained, and established a list of DMRs potentially association with sheep body size Overall design: Blood DNA methylation level of main Chinese Mongolian sheep was generated by deep sequencing. Subpopulation (breed) of Chinese Mongolian sheep: UQ: Ujumqin sheep Tan: Tan sheep StH: Small-tailed-Han sheep Hu: Hu sheep

INSTRUMENT(S): Illumina HiSeq 2000 (Ovis aries)

SUBMITTER: Jiaxue Cao  

PROVIDER: GSE62345 | GEO | 2016-09-28



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Sub-populations of Chinese Mongolian sheep exhibit significant variance in body mass. In the present study, we sequenced the whole genome DNA methylation in these breeds to detect whether DNA methylation plays a role in determining the body mass of sheep by Methylated DNA immunoprecipitation - sequencing method. A high quality methylation map of Chinese Mongolian sheep was obtained in this study. We identified 399 different methylated regions located in 93 human orthologs, which were previously  ...[more]

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