Dataset Information


M-CGH data from Bacillus subtilis strains from both subspecies and Bacillus vallismortis

ABSTRACT: This series represents the work described in the publication Bacillus subtilis Genome Diversity by Earl et al. (Journal of Bacteriology, accepted) Keywords: comparative genomic hybridization Overall design: The aim of this study was to examine genome diversity among Bacillus subtilis species members. Strains were chosen from within both recognized subspecies and one close relative, Bacillus vallismortis.

INSTRUMENT(S): Bacillus subtilis oligonucleotide array print #2

SUBMITTER: Ashlee Earl  

PROVIDER: GSE6498 | GEO | 2006-12-13



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Bacillus subtilis genome diversity.

Earl Ashlee M AM   Losick Richard R   Kolter Roberto R  

Journal of Bacteriology 20061117 3

Microarray-based comparative genomic hybridization (M-CGH) is a powerful method for rapidly identifying regions of genome diversity among closely related organisms. We used M-CGH to examine the genome diversity of 17 strains belonging to the nonpathogenic species Bacillus subtilis. Our M-CGH results indicate that there is considerable genetic heterogeneity among members of this species; nearly one-third of Bsu168-specific genes exhibited variability, as measured by the microarray hybridization i  ...[more]

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