Genome wide extracellular signal-regulated kinase (ERK) pathway components interaction with human genome

ABSTRACT: Several recent studies, including ours, show that most components of signal transduction cascades including the extracellular signal-regulated protein kinase (ERK), that once were thought to act predominantly in cytoplasm, are in fact recruited to chromatin and are integral components of transcriptional complexes. However, their distribution along whole genome remains uncovered. Here we investigate genome wide recruitment of the ERK pathway components using chromatin immunoprecipitations (ChIP) followed by deep sequencing, ChIP-Seq.

ORGANISM(S): Homo sapiens

PROVIDER: GSE65323 | GEO | 2016/08/18

SECONDARY ACCESSION(S): PRJNA273670

REPOSITORIES: GEO