Transcriptomics

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MRNA profiling of human Multipotent Adipose-Derived Stem (hMADS) cells transfected with miR-29a and subjected to adipocyte differentiation


ABSTRACT: The human microRNA hsa-miR-29a is a member of the miR-29 family of microRNAs, which is expressed in the adipogenic lineage. To identify putative direct target mRNAs of the miR-29 family, and to get an idea about potential functions of the miR-29 family in adipocyte development, we transfected human Multipotent Adipose-Derived Stem (hMADS) cells with miR-29a mimics (leading to elevation of intracellular levels of mature miR-29a). Subsequently, gene expression profiling was performed for hMADS cells at day 0 (48 h after transfection) and at day 3, i.e. 3 days after adipocyte differentiation was induced by a chemically defined medium.

ORGANISM(S): Homo sapiens

PROVIDER: GSE65704 | GEO | 2019/01/23

REPOSITORIES: GEO

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