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Single cell RNA-seq analysis of sensory neurons reveal diverse injury responses after sciatic nerve transection

ABSTRACT: We reported the gene expression analysis of different types of sensory neuron with peripheral nerve transection treatment on single cell level. We found substantial variation between myelinated large diameter neurons and small diameter nonpeptidergic nociceptors, in both terms of regeneration response genes regulation as well as fraction of cells respond to nerve injury.

ORGANISM(S): Mus musculus

PROVIDER: GSE71453 | GEO | 2016/08/26

SECONDARY ACCESSION(S): PRJNA291276

REPOSITORIES: GEO

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