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Profiling of Brat associated mRNAs from Drosophila embryos by RIP-CHIP

ABSTRACT: The Drosophila TRIM-NHL protein Brain tumor (Brat) plays important roles during early embryogenesis, in cell fate decisions, during neurogenesis and in mature neurons. Brat is an RNA-binding protein and functions as translational repressor. However, which RNAs Brat regulates and how RNA-binding specificity is achieved, is unknown. Using RNA-Immunoprecipitation we identify Brat-bound mRNAs in Drosophila embryos and define a consensus binding motif. Microarrays were used to profile Brat-associated RNAs from fly embryos.

ORGANISM(S): Drosophila melanogaster

PROVIDER: GSE71663 | GEO | 2015/11/13

SECONDARY ACCESSION(S): PRJNA291758

REPOSITORIES: GEO

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