Genomics

Dataset Information

17

Transcriptome analysis of liver and kidneys of rats chronically fed a NK603 Roundup-tolerant genetically modified maize


ABSTRACT: This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series

INSTRUMENT(S): [RaGene-2_0-st] Affymetrix Rat Gene 2.0 ST Array [transcript (gene) version]

SUBMITTER: Matthew Arno  

PROVIDER: GSE73888 | GEO | 2016-10-01

SECONDARY ACCESSION(S): GSE73884PRJNA298337 GSE73886S-EPMC5306156

REPOSITORIES: GEO

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Publications

Transcriptome and metabolome analysis of liver and kidneys of rats chronically fed NK603 Roundup-tolerant genetically modified maize.

Mesnage Robin R   Arno Matthew M   Séralini Gilles-Eric GE   Antoniou Michael N MN  

Environmental sciences Europe 20170207 1


<h4>Background</h4>A previous 2-year rat feeding trial assessing potential toxicity of NK603 Roundup-tolerant genetically modified maize revealed blood and urine biochemical changes indicative of liver and kidney pathology. In an effort to obtain deeper insight into these findings, molecular profiling of the liver and kidneys from the same animals was undertaken.<h4>Results</h4>Transcriptomics showed no segregation of NK603 maize and control feed groups with false discovery rates ranging from 43  ...[more]

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