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Hydroxychloroquine inhibits responses to group A streptococcus in peripheral blood mononuclear cells

ABSTRACT: Immune responses to group A streptococcus in humans can lead to the development of acute rheumatic fever and rheumatic heart disease. Immune pathways that are activated by group A streptococcus are potential targets for inhibiting autoimmune responses to group A streptococcus. This experiment tests the impact of the drug hydroxychloroquine on immune responses to group A streptococcus in peripheral blood mononuclear cells

ORGANISM(S): Homo sapiens

PROVIDER: GSE74235 | GEO | 2016/10/21

SECONDARY ACCESSION(S): PRJNA299596

REPOSITORIES: GEO

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