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Expression data from the mouse ES cell-derived differentiated cells treated with or without MPA

ABSTRACT: Mycophenolic acid (MPA), effectively promoted ES cell pancreatic differentiation with a concomitant reduction of neuronal cells. The targets of MPA were investigated by microarray analysis of cells treated on day 5 with MPA and harvested on day 6 and 8.

ORGANISM(S): Mus musculus

PROVIDER: GSE78797 | GEO | 2016/03/02

SECONDARY ACCESSION(S): PRJNA313942

REPOSITORIES: GEO

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Expression data from the mouse ES cell-derived differentiated cells treated with or without MPA

Project description:Mycophenolic acid (MPA), effectively promoted ES cell pancreatic differentiation with a concomitant reduction of neuronal cells. The targets of MPA were investigated by microarray analysis of cells treated on day 5 with MPA and harvested on day 6 and 8. Cells were harvested for RNA extraction and hybridization on Affymetrix microarrays. We performed gene expression profiles of differentiated mouse ES cells treated with or without 2 microM MPA at day5, 6, and 8

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Expression data from undifferentiated and differentiated mouse female ES cells PGK12.1

Project description:Affymetrix 430 2.0 mouse arrays were used for expression analyses in undifferentiated and differentiated PGK12.1 ES cells. We found that the X:autosome expression ratios calculated from the mean expression values of X-linked and autosomal genes from microarrays was ~1.4 in undifferentiated female ES cells and then decreased to 1.2 in PGK12.1 cells after 15-day embryoid body differentiation. Thus, a substantial level of X upregulation is already evident in these ES cells prior to differentiation. Our findings based on Affymetrix expression arrays are consistent with microarray analysis from other labs and our RNA-seq analysis of mouse female PGK12.1 ES cells.

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Deferribacter sp. MPA-C3

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