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Response to low-dose cortisol treatment in zebrafish embryos [larvae]

ABSTRACT: Chronic early life stress increases adult susceptibility to numerous health problems linked to chronic inflammation. One way that this may occur is via glucocorticoid-induced developmental programming. To gain insight into such programming we treated zebrafish embryos with 1 micromolar cortisol and examined the effects on larvae. Treated larvae had elevated whole-body cortisol and glucocorticoid signaling, and up-regulated genes associated with defense response and immune system processes.

ORGANISM(S): Danio rerio

PROVIDER: GSE80221 | GEO | 2016/06/01

SECONDARY ACCESSION(S): PRJNA318296

REPOSITORIES: GEO

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Response to low-dose cortisol treatment in zebrafish embryos [larvae]

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