Transcriptomics,Genomics

Dataset Information

150

Differentially expressed genes in certinib-resistant NB-1 xenografts


ABSTRACT: The goal of this study is to elucidate the molecular mechanism that allowed NB-1 xenograft tumors to grow out in the presence of continued ALK inhibition. Poly(A)-selected RNA was extracted from tissues of NB-1 tumors that progressed on ceritinib treatment and those treated with a vehicle to identify differentially expressed genes between these two groups. Overall design: mRNA profiles of NB-1 xenograft tumors that progressed on ceritinib treatment and those treated with a vehicle were generated by RNA sequencing, in duplicate, using Illumina HiSeq 2500.

INSTRUMENT(S): Illumina HiSeq 2500 (Homo sapiens)

SUBMITTER: Fang Li 

PROVIDER: GSE82143 | GEO | 2016-09-01

SECONDARY ACCESSION(S): PRJNA324126

REPOSITORIES: GEO

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