Dataset Information


Expression data from Rspo1-null differentiating primary myoblasts

ABSTRACT: Regeneration of the adult skeletal muscle tissue relies on a population of muscle stem cells called satellite cells. During tisse repair, satellite cells exhibit active canonical Wnt/beta-catenin signaling. Rspo1 is a modulator of Wnt signaling in many tissue, and is expressed by muscle progenitor cells. To identify genes that become transcribed following activation of the Wnt/β-Catenin pathway in satellite cells, we performed microarray analysis of primary myoblasts expressing an active form of beta-catenin Overall design: Primary myoblasts were prepared from the limb muscles of wild-type and Rpos1-null mice. RNA was extracted from two independent cultures for each conditions.

INSTRUMENT(S): [MoGene-2_0-st] Affymetrix Mouse Gene 2.0 ST Array (mogene20st_Mm_ENTREZG_19)

SUBMITTER: Fabien Le Grand  

PROVIDER: GSE84016 | GEO | 2017-01-01



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