Dataset Information


NIA/NIH AGEMAP Brain Regions

ABSTRACT: This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series


SUBMITTER: Kevin G Becker  

PROVIDER: GSE8426 | GEO | 2007-12-28

SECONDARY ACCESSION(S): GSE8413 GSE8417 GSE8409 GSE8414 GSE8418PRJNA101483 GSE8410 GSE8411 GSE8415 GSE8419 GSE8412


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Gene expression atlas of the mouse central nervous system: impact and interactions of age, energy intake and gender.

Xu Xiangru X   Zhan Ming M   Duan Wenzhen W   Prabhu Vinayakumar V   Brenneman Randall R   Wood William W   Firman Jeff J   Li Huai H   Zhang Peisu P   Ibe Carol C   Zonderman Alan B AB   Longo Dan L DL   Poosala Suresh S   Becker Kevin G KG   Mattson Mark P MP  

Genome biology 20070101 11

The structural and functional complexity of the mammalian central nervous system (CNS) is organized and modified by complicated molecular signaling processes that are poorly understood.We measured transcripts of 16,896 genes in 5 CNS regions from cohorts of young, middle-aged and old male and female mice that had been maintained on either a control diet or a low energy diet known to retard aging. Each CNS region (cerebral cortex, hippocampus, striatum, cerebellum and spinal cord) possessed its o  ...[more]

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