Ontology highlight
ABSTRACT:
INSTRUMENT(S): Illumina HiSeq 2000 (Homo sapiens)
SUBMITTER: Chuan He
PROVIDER: GSE86214 | GEO | 2016-09-15
SECONDARY ACCESSION(S): PRJNA340948
REPOSITORIES: GEO
Action | DRS | |||
---|---|---|---|---|
GSE86214_YTHDF3_PAR-CLIP.xlsx | Xlsx | |||
GSE86214_YTHDF3_RIP.xlsx | Xlsx | |||
GSE86214_siYTHDF3_RiboProfile.xlsx | Xlsx | |||
GSE86214_siYTHDF3_YTHDF12RIP.xlsx | Xlsx |
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Cell research 20170120 3
N<sup>6</sup>-methyladenosine (m<sup>6</sup>A) is the most abundant internal modification in eukaryotic messenger RNAs (mRNAs), and plays important roles in cell differentiation and tissue development. It regulates multiple steps throughout the RNA life cycle including RNA processing, translation, and decay, via the recognition by selective binding proteins. In the cytoplasm, m<sup>6</sup>A binding protein YTHDF1 facilitates translation of m<sup>6</sup>A-modified mRNAs, and YTHDF2 accelerates th ...[more]