Genomics

Dataset Information

32

Gene expression analysis of enSLiT KO cells against Salmonella infection


ABSTRACT: Eukaryotic genomes are pervasively transcribed, resulting in the production of many unstable nuclear long noncoding RNAs such as nuclear Short-Lived noncoding Transcripts (nSLiTs). However, the biological significance and turnover mechanism of nSLiTs are largely unknown. We used microarrays to detail the global program of gene expression that is regulated by enSLiT upon Salmonella infection Overall design: To assess the role of enSLiT against Salmonella infection, we knockout enSLiT07573 by using CRISPR/Cas9. KO was performed replicate for each transcripts. We comparied Salmonella infected/not infected HeLa cells and KO cells. All data was obtained biological triplicate.

INSTRUMENT(S): Agilent-072363 SurePrint G3 Human GE v3 8x60K Microarray 039494 [Probe Name Version]

SUBMITTER: Yayoi Fukuoka  

PROVIDER: GSE87754 | GEO | 2016-10-08

SECONDARY ACCESSION(S): PRJNA347346

REPOSITORIES: GEO

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