Genomics

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Profiling of Ileal Transcriptome in Pediatric Crohn Disease


ABSTRACT: We report ileal gene expression at diagnosis in a cohort of 210 treatment-naïve patients of pediatric Crohn's disease and 35 non-IBD controls from the RISK study. After three years of follow-up after diagnosis, 27 of the CD patients progressed to complicated disease (B2 and/or B3). We aim to test whether Transcriptional Risk Scores helps to distinguish between patient subgroups, improving the predictive power gained from Genetic Risk Scores.

ORGANISM(S): Homo sapiens

PROVIDER: GSE93624 | GEO | 2017/06/20

SECONDARY ACCESSION(S): PRJNA361305

REPOSITORIES: GEO

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