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Control of plant cell fate transitions by transcriptional and hormonal signals

ABSTRACT: This SuperSeries is composed of the SubSeries listed below.

ORGANISM(S): Arabidopsis thaliana

PROVIDER: GSE94311 | GEO | 2017/11/15

SECONDARY ACCESSION(S): PRJNA369320

REPOSITORIES: GEO

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Control of plant cell fate transitions by transcriptional and hormonal signals.

Project description: Not available

| S-EPMC5693117 | biostudies-literature

Control of plant cell fate transitions by transcriptional and hormonal signals [ChIP-seq]

Project description:Plant meristems carry pools of continuously active stem cells, whose activity is controlled by developmental and environmental signals. After stem cell division, daughter cells that exit the stem cell domain acquire transit amplifying cell identity before they are incorporated into organs and differentiate. In this study, we used an integrated approach to elucidate the role of HECATE (HEC) genes in regulating developmental trajectories of shoot stem cells in Arabidopsis thaliana. Our work reveals that HEC function stabilizes cell fate in distinct zones of the shoot meristem thereby controlling the spatio-temporal dynamics of stem cell differentiation. Importantly, this activity is concomitant with the local modulation of cellular responses to cytokinin and auxin, two key phytohormones regulating cell behaviour. Mechanistically, we show that HEC factors directly modulate auxin signal transduction by physical interaction with MONOPTEROS (MP), a key regulator of auxin signalling, and thus interfere with the autocatalytic stabilization of auxin signalling.

2017-11-15 | GSE94307 | GEO