Transcriptomics,Genomics

Dataset Information

151

RNA-seqanalysis of deinococcus wild-type and mazEF mutant strains after MMC treatment


ABSTRACT: RNA-seq was used to analysis of mazEF toxin-antitoxin system mediated post-transcriptional inhibition through its endoribonuclease activity. DNA damage agents ,such as MMC, activates the mazEF system leading to cells growth arrest. In the present study, results reveal that a larger number of genes involved in amino acid and carbohydrate metabolism, ion transport and transcription was down-regulated in the wild-type compared with the mazEF-dr mutant. Overall design: Total RNAs were extrated from wild-type deinococcus radiodurans and mazEF mutant strain with or without MMC treatment.

INSTRUMENT(S): Illumina HiSeq 4000 (Deinococcus radiodurans)

SUBMITTER: Tao Li  

PROVIDER: GSE97563 | GEO | 2017-04-11

SECONDARY ACCESSION(S): PRJNA382319

REPOSITORIES: GEO

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