Transcriptomics,Genomics

Dataset Information

32

Human normal oral keratinocytes (NOK) siRNA and Human epidermal keratinocytes (HEK) overexpression RNA-Seq


ABSTRACT: Transcriptome of si-RNA transfected NOK cells and adenovirus-transduced HEK cells Overall design: mRNA profiles of HEK (human epidermal keratinocytes) transduced with adenoviruses and NOK (human normal oral keratinocytes) transfected with siRNAs.

INSTRUMENT(S): Illumina HiSeq 2000 (Homo sapiens)

ORGANISM(S): Homo sapiens  

SUBMITTER: Maria Irene Morasso  

PROVIDER: GSE97616 | GEO | 2018-08-07

REPOSITORIES: GEO

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Publications


Oral mucosal wound healing has long been regarded as an ideal system of wound resolution. However, the intrinsic characteristics that mediate optimal healing at mucosal surfaces are poorly understood, particularly in humans. We present a unique comparative analysis between human oral and cutaneous wound healing using paired and sequential biopsies during the repair process. Using molecular profiling, we determined that wound-activated transcriptional networks are present at basal state in the or  ...[more]

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