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Signature of coevolution between determinants of defense and life span in Arabidopsis thaliana

ABSTRACT: The selective impact of pathogen epidemics on host defenses can be strong but remains transient. By contrast, life-history shifts can durably and continuously modify the balance between costs and benefits, which arbitrates the evolution of host defenses. Their impact, however, has seldom been documented. Here, we show with a simple mathematical model that the selective advantage of the defense system is expected to decrease with decreasing life span. We further document that, in natural populations of the model plant system Arabidopsis thaliana, the expression level of defense genes correlate positively with flowering time, a proxy for the length of vegetative life span. Using a genetic strategy to partition life span-dependent and –independent defense genes, we demonstrate that this positive co-variation is not explained by the pleiotropic action of major regulatory genes controlling both defense and life span. In agreement with our model, this study reveals that natural selection has likely assembled alleles promoting lower expression of defense genes with alleles decreasing the duration of vegetative life span in natural populations of A. thaliana. This is the first study demonstrating that life history evolution has a pervasive impact on the evolution of host immunity.

ORGANISM(S): Arabidopsis thaliana

PROVIDER: GSE97664 | GEO | 2017/05/31

SECONDARY ACCESSION(S): PRJNA382583

REPOSITORIES: GEO

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Arabidopsis thaliana

Project description:Signature of coevolution between determinants of defense and life span in Arabidopsis thaliana

| PRJNA382583 | ENA