Dataset Information


Gene expression kinetics in Raw264.7 Cells following treatment with potential probiotics strains Lactobacillus acidophilus MTCC-10307 and Bacillus clausii MTCC-8326 : NT (Time matched untreated cells) vs. Probiotics treated cells

ABSTRACT: Gene expression kinetics in RAW 264.7 cells on treatment with Lactobacillus acidophilus MTCC-10307 and Bacillus clausii MTCC-8326. Overall design: Eight conditions of the expriment, Untreated RAW 264.7 cells (NT) vs. treatment with Lactobacillus acidophilus MTCC-10307 and Bacillus clausii MTCC-8326 separately at MOI of 100 with 4 time points. Biological replicates: 3 in each case (Equal amount of total RNA from each replicate pulled together for microarray).

INSTRUMENT(S): Agilent-014868 Whole Mouse Genome Microarray 4x44K G4122F (Feature Number version)

SUBMITTER: Biswaranjan Pradhan  

PROVIDER: GSE98701 | GEO | 2017-05-10



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Comparative Analysis of the Effects of Two Probiotic Bacterial Strains on Metabolism and Innate Immunity in the RAW 264.7 Murine Macrophage Cell Line.

Pradhan Biswaranjan B   Guha Dipanjan D   Ray Pratikshya P   Das Debashmita D   Aich Palok P  

Probiotics and antimicrobial proteins 20160601 2

Probiotic and potential probiotic bacterial strains are routinely prescribed and used as supplementary therapy for a variety infectious diseases, including enteric disorders among a wide range of individuals. While there are an increasing number of studies defining the possible mechanisms of probiotic activity, a great deal remains unknown regarding the diverse modes of action attributed to these therapeutic agents. More precise information is required to support the appropriate application of p  ...[more]

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