Ontology highlight
ABSTRACT:
OTHER RELATED OMICS DATASETS IN: PRJNA386487
INSTRUMENT(S): Illumina MiSeq (Planococcus halocryophilus)
SUBMITTER: Felix Georg Maria Ernst
PROVIDER: GSE98874 | GEO | 2017-11-03
SECONDARY ACCESSION(S): PRJNA386487
REPOSITORIES: GEO
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GSE98874_RAW.tar | Raw | |||
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RNA biology 20171121 1
Cold adaptation is an evolutionary process that has dramatic impact on enzymatic activity. Increased flexibility of the protein structure represents the main evolutionary strategy for efficient catalysis and reaction rates in the cold, but is achieved at the expense of structural stability. This results in a significant activity-stability tradeoff, as it was observed for several metabolic enzymes. In polymerases, however, not only reaction rates, but also fidelity plays an important role, as the ...[more]