Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

GNPS_P rubens P03MB2_Neo Oct 2024

ABSTRACT: Untargeted metabolomics of an endophtic fungus, Penicillium rubens exhibiting anti-HIV activity

INSTRUMENT(S): LCMS-9030

ORGANISM(S): Penicillium Rubens (ncbitaxon:1108849)

SUBMITTER: Sizwe Ndlovu

PROVIDER: MSV000097382 | GNPS | Wed Mar 19 14:37:00 GMT 2025

REPOSITORIES: GNPS

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

Transcriptomic analysis of fungus Penicillium decumbens and brlA deletion strains in different culture medium

Project description:Transcriptomic analysis of fungus Penicillium decumbens and brlA deletion strains in liquid medium and solid medium respectivelly Examination of differential gene expressions by Penicillium decumbens strains 114-2 and brlA deletion stains in liquid medium and solid medium

2013-04-09 | E-GEOD-45855 | biostudies-arrayexpress

Transcriptomic analysis of fungus Penicillium decumbens and brlA deletion strains in different culture medium

Project description:Transcriptomic analysis of fungus Penicillium decumbens and brlA deletion strains in liquid medium and solid medium respectivelly

2013-04-09 | GSE45855 | GEO

Expression data from Arabidopsis thaliana leaves treated with BrvC

Project description:Brevicompanines are natural products isolated from the culture filtrate of the fungus Penicillium brevicompactum. They showed plant growth regulating properties in several species including lettuce, rice or Arabidopsis thaliana. We used microarrays to gather information about the reprogramming of gene transcription when Arabidopsis leaves were treated with Brevicompanine C (BrvC) that showed significant activity in plant growth assays.

2016-11-22 | GSE90096 | GEO

754cd689-b994-46a3-a3d2-c9b3fbc55ebf - samples

Project description:Full clinical data for a cohort of 199 individuals with acute coronary syndrome. Untargeted serum metabolomics using the Metabolon platform for individuals with ACS (n=156). Serum metabolomics using the Nightingale Health (NMR) platform for individuals with ACS and controls (ACS, n=191; controls, n=961).

| EGAD00001007724 | EGA

Macrophages show unprecedented anti-HIV activity in HIV-infected iHMD-NSG mice

Project description:Macrophages show unprecedented anti-HIV activity in HIV-infected iHMD-NSG mice

| PRJNA1120898 | ENA

Bacillus-Fungus interaction IV

Project description:Non-targeted metabolomics of bacteria fungus interaction and bio-activity guided fractions.

2018-12-05 | MSV000083183 | MassIVE

Effect of Nudt7 overexpression on the global transcriptome of mouse liver in the fasted state

Project description:RNAseq analysis was conducted to complement the targeted and untargeted metabolomics analysis of livers overexpressing the CoA-degrading enzyme Nudt7 or GFP (control). Lipid metabolism requires coenzyme A (CoA), which is found in multiple subcellular compartments including the peroxisomes. In the liver, CoA levels are dynamically adjusted between the fed and fasted states. The elevation in CoA levels that occurs during fasting is driven by increased synthesis but also correlates with decreased expression of Nudt7, the major CoA-degrading enzyme in the liver. Nudt7 resides in the peroxisomes and we overexpressed this enzyme in mouse livers to determine its effect on the size and composition of the hepatic CoA pool in the fed and fasted states. Nudt7 overexpression did not change total CoA levels but decreased the concentration of short-chain acyl-CoAs and choloyl-CoA in fasted livers, when endogenous Nudt7 activity was lowest. The effect on these acyl-CoAs correlated with a significant decrease in the hepatic bile acid content and in the rate of peroxisomal fatty acid oxidation, as estimated by targeted and untargeted metabolomics, combined with the measurement of fatty acid oxidation in intact hepatocytes. Identification of the CoA species and metabolic pathways affected the overexpression on Nudt7 in vivo supports the conclusion that the nutritionally-driven modulation of Nudt7 activity could contribute to the regulation of the peroxisomal CoA pool and peroxisomal lipid metabolism.

2019-03-08 | GSE125237 | GEO

CARDIA Multi-omics Obesity & CVD Substudy – Year 20 Untargeted Metabolomics Data

Project description:CARDIA Multi-omics Obesity & CVD Substudy – Year 20 Untargeted Metabolomics Data

| PRJNA1122871 | ENA

CARDIA Multi-omics Obesity & CVD Substudy – Year 20 Untargeted Metabolomics Data

Project description:CARDIA Multi-omics Obesity & CVD Substudy – Year 20 Untargeted Metabolomics Data

| PRJNA1122872 | ENA

The effects of transcriptional activator engineering on the transcriptome of Penicillium oxalicum

Project description:The filamentous fungus Penicillium oxalicum can secret various enzymes for efficient saccharification of plant biomass materials. Expression of the constitutively active forms of transcriptional activators ClrB, XlnR and AraR could trigger the production of different sets of lignocellulolytic enzymes. Here, the transcriptomes of the three engineered strains were compared with that of wild type in the medium without carbon source.

2020-12-05 | GSE162657 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data