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The proteomic landscape of triple-negative breast cancer


ABSTRACT: Data from ProteomicsDB, ID: PRDB004167. Experiment: MCF10A_Trypsin_rep1, file: folder summary. Published as part of Cell Rep. 2015 Apr 15. pii: S2211-1247(15)00341-1 . From the Abstract: {{i}} Triple-negative breast cancer is a heterogeneous disease characterized by poor clinical outcomes and a shortage of targeted treatment options. To discover molecular features of triple-negative breast cancer, we performed quantitative proteomics analysis of twenty human-derived breast cell lines and four primary breast tumors ... {{/i}}

INSTRUMENT(S): Instrument

ORGANISM(S): Homo_sapiens_viruses, Human_female

DISEASE(S): Not Available

SUBMITTER: Lawrence RT, et al.  

PROVIDER: GPM32320015247 | GPMDB |

REPOSITORIES: GPMDB

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Triple-negative breast cancer is a heterogeneous disease characterized by poor clinical outcomes and a shortage of targeted treatment options. To discover molecular features of triple-negative breast cancer, we performed quantitative proteomics analysis of twenty human-derived breast cell lines and four primary breast tumors to a depth of more than 12,000 distinct proteins. We used this data to identify breast cancer subtypes at the protein level and demonstrate the precise quantification of bio  ...[more]

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