Executioner Caspase-3 and 7 Deficiency Reduces Myocyte Number in the Developing Mouse Heart.

ABSTRACT: Data from PeptideAtlas, [[http://www.peptideatlas.org/PASS/PASS00689 PASS00689]]. File: JAL_DanSanc_Hrt_iTRAQ_Fr6.mzml. Published as part of PLoS One. 2015 Jun 29;10(6):e0131411 . From the Abstract: {{i}} Executioner caspase-3 and -7 are proteases promoting cell death but non-apoptotic roles are being discovered. The heart expresses caspases only during development, suggesting they contribute to the organ maturation process. Therefore, we aimed at identifying novel functions of caspases in heart development. We induced simultaneous deletion of executioner caspase-3 and -7 in the mouse myocardium and studied its effects ... {{/i}}

INSTRUMENT(S): Instrument

ORGANISM(S): Mus_musculus_viruses, Mouse

DISEASE(S): Not Available

SUBMITTER: Cardona M, et al.  

PROVIDER: GPM32320017677 | GPMDB |

REPOSITORIES: GPMDB