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Deep Proteomic Profiling of Vasopressin-Sensitive Collecting Duct Cells


ABSTRACT: Data from ProteomeXchange, PXD ID: PXD002434. File: 335.mzml. Published as part of Am J Physiol Cell Physiol. 2015 Aug 26:ajpcell.00214.2015 and Am J Physiol Cell Physiol. 2015 Aug 26:ajpcell.00213.2015

INSTRUMENT(S): Instrument

ORGANISM(S): Mus_musculus_viruses, Mouse

DISEASE(S): Not Available

SUBMITTER: Yang CR, et al.  

PROVIDER: GPM32320018959 | GPMDB |

REPOSITORIES: GPMDB

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Publications

Deep proteomic profiling of vasopressin-sensitive collecting duct cells. II. Bioinformatic analysis of vasopressin signaling.

Yang Chin-Rang CR   Raghuram Viswanathan V   Emamian Milad M   Sandoval Pablo C PC   Knepper Mark A MA  

American journal of physiology. Cell physiology 20150826 12


Vasopressin controls osmotic water transport in the renal collecting duct through regulation of aquaporin-2 (AQP2). We carried out bioinformatic analysis of quantitative proteomic data from the accompanying article to investigate the mechanisms involved. The experiments used stable isotope labeling by amino acids in cell culture in cultured mpkCCD cells to quantify each protein species in each of five differential-centrifugation (DC) fractions with or without the vasopressin analog 1-desamino-8-  ...[more]

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