Peptidome analysis of cerebrospinal fluid in neonates with hypoxic-ischemic brain damage
Ontology highlight
ABSTRACT:
ORGANISM(S): Homo Sapiens
SUBMITTER: 
Jie Qiu
PROVIDER: PXD017797 | iProX | Sun Mar 01 00:00:00 GMT 2020
REPOSITORIES: iProX
Publications
Peptidome analysis of cerebrospinal fluid in neonates with hypoxic-ischemic brain damage.
Hou Xuewen X Yuan Zijun Z Wang Xuan X Cheng Rui R Zhou Xiaoguang X Qiu Jie J
Molecular brain 20201002 1
Hypoxic-ischemic brain injury (HIBD) causes neonatal death and serious neurological disability; however, there are currently no promising therapies for it excepting cooling. Therefore, in this study, we used peptidome analysis to identify differentially expressed peptides in cerebrospinal fluid (CSF) of neonates with HIBD or controls, which may give a foundation for finding new promising drugs of neonatal HIBD. CSF samples were collected from neonates with HIBD (n = 4) or controls (n = 4). ITRAQ ...[more]
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