Proteomics

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Efficient inactivation of virus in water by damaging viral protein and genome using pulsed corona discharge plasma


ABSTRACT: This study first evaluated the inactivation efficacy of PCDP using spring viremia of carp virus (SVCV) as models for viruses in water. As for the mechanism of virus inactivation, we used molecular tools and high-resolution mass spectrometry to determine reactions of viral proteins and genome after inactivation by PCDP.

ORGANISM(S): Carp Sprivivirus

SUBMITTER: Gaoxue Wang  

PROVIDER: PXD024027 | iProX | Sat Feb 06 00:00:00 GMT 2021

REPOSITORIES: iProX

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Publications

Inactivation efficacy and mechanism of pulsed corona discharge plasma on virus in water.

Song Kaige K   Wang Hui H   Jiao Zhi Z   Qu Guangzhou G   Chen Weichao W   Wang Gaoxue G   Wang Tiecheng T   Zhang Zengqiang Z   Ling Fei F  

Journal of hazardous materials 20210812


The presence of viruses in water is a major risk for human and animal health due to their high resistance to disinfection. Pulsed corona discharge plasma (PCDP) efficiently inactivates bacteria by causing damage to biological macromolecules, but its effect on waterborne virus has not been reported. This study evaluated the inactivation efficacy of PCDP to viruses using spring viremia of carp virus (SVCV) as a model. The results showed that 4-log<sub>10</sub> reduction of SVCV infectivity in cell  ...[more]

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