Project description:EndoC-betaH1 cells were treated with IL-1b and IFN-g for 48h, digested with trypsin, multiplexed with TMT-10, fractionated by high pH reverse-phase chromatography and analyzed by tandem LC-MS/MS.
Project description:The metabolomics data from a multiomics study of the cellular response to a KRASG12D inhibitor, MRTX1133. This repository will accompany the completed bulk pasedDIA analysis of cells treated with inhibitor and approximately 3,000 single cells treated with the same dose and conditions.
Project description:To identify gene expression changes associated with treatment of EVs from MDA-MB-231 [231] and MCF10A [10A] cells) in NIH3T3 cells, we analyzed RNA isolated from PBS- or EV-treated NIH3T3 cells. Gene expression in NIH3T3 cells treated with EV from MDA-MB-231 cells was compared to cells treated with PBS or EV from MCF10A cells, both of which served as controls in this experiment.
Project description:The goal of these ATAC-seq experiments was to determine changes in chromatin accesiblity caused by Il1a and Osm ligand treatment of mouse BCC cells at 48h timepoint versus PBS control
Project description:The objective of this experiment was to determine the DNA binding sites of transcription factor NFKB1 in mouse BCC cells upon Il1a and Osm ligand treatment at 48h timepoint versus PBS control
Project description:To characterize the potential molecular pathway(s) affected by iron treatment and identify the one(s) responsible for C3 induction, we performed a whole genome microarray on untreated ARPE-19 cells and cells treated with 250 μM FAC for 48h/2d.
Project description:The goal of these RNA-seq experiments was to determine transcriptomic gene expression changes caused by Il1 or Osm (or both) treatments of mouse BCC cells at 24h and 48h timepoints versus PBS control