Proteomics of exosomes derived from cisplatin-induced dormant A549 cells

ABSTRACT: Lung cancer is the leading cause of cancer-related deaths worldwide. Chemotherapy kills most cancer cells, however, the residual cells enter into dormant state. The dormant cancer cells can be reactivated under specific circumstances. Tumor-derived exosomes are the main mediators of tumorigenesis. We are aiming to elucidate the roles of exosomes from cisplatin-induced dormant lung cancer cells in the tumor recurrence and metastasis. We performed differential proteome in dormant A549 cell- and A549 cell-derived exosomes.

ORGANISM(S): Homo Sapiens

SUBMITTER: Juanjuan Xiang  

PROVIDER: PXD037475 | iProX | Mon Oct 17 00:00:00 BST 2022

REPOSITORIES: iProX