Proteomics

Dataset Information

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Identification and validation of differential proteins in liver tissues of New Zealand rabbits at different months of age


ABSTRACT: Rabbit hemorrhagic disease is an acute and highly fatal infectious disease caused by rabbit hemorrhagic disease virus. The mortality rate of adult rabbits is more than 90 %, but 2-week-old young rabbits are not affected. Based on the differences in the susceptibility of young rabbits and adult rabbits to RHDV, TMT proteomics technology was used to detect and quantitatively analyze the liver tissue proteins of young rabbits (2 weeks old) and adult rabbits (6 months old). 4353 proteins were quantitatively obtained from the liver tissues of young rabbits and adult rabbits, and 821 differential proteins were screened. Among them, 294 proteins were significantly upregul-ated and 527 proteins were significantly down-regulated in the liver tissues of adult rabbits compared with young rabbits.

ORGANISM(S): Oryctolagus Cuniculus

SUBMITTER: Jialin Bai  

PROVIDER: PXD045206 | iProX | Wed Nov 30 00:00:00 GMT 2022

REPOSITORIES: iProX

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