Bacterial Protoplast-Derived Nanovesicles Carrying CRISPR Cas9 Tools Efficiently Re-educate Tumor-Associated Macrophages for Cancer Immunotherapy

ABSTRACT: we developed an in vivo CRISPR-Cas9 genome editing system that targets tumor-associated macrophages (TAMs) via bacterial protoplast-derived nanovesicles (NVs) decorated with a pH-responsive PEG conjugated polymer and galactosamine-conjugated ligand

ORGANISM(S): Escherichia Coli Bl21(de3)

SUBMITTER: Junfeng Zhang  

PROVIDER: PXD045507 | iProX | Wed Sep 20 00:00:00 GMT+01:00 2023

REPOSITORIES: iProX