Cell fate decision by a morphogen-transcription factor-chromatin modifier axis
Ontology highlight
ABSTRACT:
ORGANISM(S): Mus Musculus
SUBMITTER: 
Duanqing Pei
PROVIDER: PXD051433 | iProX | Fri Apr 12 00:00:00 BST 2024
REPOSITORIES: iProX
Publications
Cell fate decision by a morphogen-transcription factor-chromatin modifier axis.
Ming Jin J Lin Lihui L Li Jiajun J Wu Linlin L Fang Shicai S Huang Tao T Fu Yu Y Liu Dong D Zhang Wenhui W Li Chen C Yang Yongzheng Y Huang Yi Y Qin Yue Y Kuang Junqi J Huang Xingnan X Guo Liman L Zhang Xiaofei X Liu Jing J Chen Jiekai J Zhao Chengchen C Wang Bo B Pei Duanqing D
Nature communications 20240729 1
Cell fate decisions remain poorly understood at the molecular level. Embryogenesis provides a unique opportunity to analyze molecular details associated with cell fate decisions. Works based on model organisms have provided a conceptual framework of genes that specify cell fate control, for example, transcription factors (TFs) controlling processes from pluripotency to immunity<sup>1</sup>. How TFs specify cell fate remains poorly understood. Here we report that SALL4 relies on NuRD (nucleosome- ...[more]
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