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Effect of oxidative stress on proteome expression in Escherichia coli

ABSTRACT: Analysis of differences in Escherichia coli proteome expression due to exogenous H2O2 exposure and genetic mutation-mediated oxidative stress.

ORGANISM(S): Escherichia Coli

SUBMITTER: Morigen

PROVIDER: PXD055835 | iProX | Fri Sep 13 00:00:00 BST 2024

REPOSITORIES: iProX

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Characterizing Common Factors Affecting Replication Initiation During H2O2 Exposure and Genetic Mutation-Induced Oxidative Stress in Escherichia coli.

Qiao Jiaxin J Zhu Weiwei W Du Dongdong D Morigen Morigen M

International journal of molecular sciences 20250325 7

Oxidative stress is prevalent in organisms, and excessive oxidative damage can trigger cell death. Bacteria have evolved multiple pathways to cope with adverse stress, including the regulation of the cell cycle. Previous studies show that non-lethal exposure to H2O2 and mutations in antioxidant enzymes suppress replication initiation in Escherichia coli. The existence of common regulatory factors governing replication initiation across diverse causes-induced oxidativ ...[more]

PMID: 40243598

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