Proteomics

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Upregulation of protein O-GlcNAcylation levels promotes zebrafish fin regeneration


ABSTRACT: LC-MS/MS was performed to identify O-GlcNAc-glycoproteins. The results demonstrated that the O-GlcNAc glycoproteins

ORGANISM(S): Danio Rerio

SUBMITTER: Jihong Cui  

PROVIDER: PXD059799 | iProX | Sat Feb 22 00:00:00 GMT 2025

REPOSITORIES: iProX

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Upregulation of Protein O-GlcNAcylation Levels Promotes Zebrafish Fin Regeneration.

Jia Liyuan L   Zheng Hanxue H   Feng Juantao J   Ding Yi Y   Sun Xiaotian X   Yu Yuan Y   Hao Xue X   Wang Junxiang J   Zhang Xinyu X   Tian Yuanfeng Y   Chen Fulin F   Cui Jihong J  

Molecular & cellular proteomics : MCP 20250304 4


As one of the most important posttranslational modifications, glycosylation participates in various cellular activities in organisms and is closely associated with many pathogeneses. It has been reported that glycosylation affects the liver, spinal cord, and heart tissue regeneration. The zebrafish fin has become a valuable model due to its high regenerative capacity. The molecular mechanism of regeneration has been a hot research topic in the field for a long time. However, studies on the influ  ...[more]

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