Proteomics

Dataset Information

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Urinary Proteomic Profiles of Anterior Cruciate Ligament Reconstruction Patients


ABSTRACT: A total of 30 ACLR patients, at least 9 months post-surgery, were recruited. Patients were divided into RTS and non-RTS groups based on their ability to return to sport, recovery to pre-injury Tegner levels, and a leg symmetry index of 85% on the single-leg hop test. Urine samples were analyzed using liquid chromatography-mass spectrometry (LC-MS) to identify differentially expressed proteins associated with RTS.

ORGANISM(S): Homo Sapiens

SUBMITTER: Xin Xu  

PROVIDER: PXD060941 | iProX | Wed Feb 19 00:00:00 GMT 2025

REPOSITORIES: iProX

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Publications

Alterations of urinary proteomic profiles are correlated with return to sport after anterior cruciate ligament reconstruction.

Zhu Ting T   Li Yuanyuan Y   Zhao Yingqi Y   Gong Yawei Y   Zhou Jingbin J   Xu Xin X  

BMC sports science, medicine & rehabilitation 20260110 1


<h4>Background</h4>Return to sport (RTS) after anterior cruciate ligament reconstruction (ACLR) remains a critical issue in sports medicine. Despite improvements in rehabilitation, many patients fail to return to their preinjury level of activity. Previous studies have primarily focused on clinical and biomechanical factors that influence RTS; however, the impact of intrinsic physiological changes, particularly urinary proteomic profiles, has not yet been fully explored. This study aimed to iden  ...[more]

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