Si-pgc-1 α LNP prevents bladder cancer metastasis by inhibiting mitochondrial biogenesis and energy metabolism in cancer cells

ABSTRACT: This study aims to explore the effect of PGC-1 α siRNA delivered by liposomal nanoparticles on cancer cells through transcriptome, proteome and metabolome technologies, so as to reveal its regulatory effect on cancer cell reprogramming and energy metabolism, so as to provide clues for the molecular mechanism of the treatment of metastatic bladder cancer.

ORGANISM(S): Mus Musculus

SUBMITTER: Hao Zhang  

PROVIDER: PXD062155 | iProX | Sat Mar 22 00:00:00 GMT 2025

REPOSITORIES: iProX