The m6A reader IGF2BP2 promotes homologous recombination-mediated DNA repair by eliminating DNA-RNA hybrids

ABSTRACT: The m6A reader IGF2BP2 and helicase DHX9 collaborate to remove DNA-RNA hybrids at DSB sites. This action facilitates RAD51 loading and homologous recombination, influencing cancer cell responses to DNA damage therapies.

ORGANISM(S): Homo Sapiens

SUBMITTER: Yang Li  

PROVIDER: PXD067817 | iProX | Thu Aug 28 00:00:00 BST 2025

REPOSITORIES: iProX