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PISA-based thermal proteome profiling of human liver tissue exposed to environmental pollutants

ABSTRACT: This study applied the Proteome Integral Solubility Alteration (PISA) approach combined with DIA-MS to characterize protein stability changes in human liver tissue exposed to environmental pollutants, including BPA, PAH, PFOS, and TMP. The work provides a proteome-wide overview of pollutant-induced thermal stability alterations and identifies potential protein targets involved in environmental hepatotoxicity.

ORGANISM(S): Homo Sapiens

SUBMITTER: Jiayin Dai

PROVIDER: PXD070215 | iProX | Mon Nov 03 00:00:00 GMT 2025

REPOSITORIES: iProX

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