Proteomics

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Mitochondria-related gene and protein changes in craniosynostosis: integrated transcriptomics and Fgfr2C361Y/+ cranial suture proteomics


ABSTRACT: This project maps mitochondria-associated molecular changes in craniosynostosis by integrating public human transcriptomes and by generating proteomic data from a genetically defined mouse model. Differential expression signals were intersected with the MitoCarta 3.0 inventory to prioritize mitochondrial candidates, and cranial suture tissue from Fgfr2C361Y/+ knock-in mice and wild-type littermates was profiled to provide protein-level support.

ORGANISM(S): Mus Musculus

SUBMITTER: XiaoLei Jin  

PROVIDER: PXD072912 | iProX | Fri Jan 09 00:00:00 GMT 2026

REPOSITORIES: iProX

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