Mechanism of targeting mitochondrial calcium signaling to promote tumor ferroptosis and activate antitumor immune response
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ABSTRACT: Elucidate the precise mechanism by which MCU regulates ferroptosis in tumor cells through modulating the acetylation of GPX4 to affect its enzymatic activity.Clarify the molecular mechanism by which MCU-regulated ferroptosis in tumor cells activates the anti-tumor immune response of CD8+ T cells.
ORGANISM(S): Homo Sapiens
SUBMITTER:
Bao Zhao
PROVIDER: PXD076544 | iProX | Thu Apr 02 00:00:00 GMT+01:00 2026
REPOSITORIES: iProX
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