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Proteomics of AC-16 cells treated with DOX

ABSTRACT: Doxorubicin (DOX) is a potent chemotherapeutic agent, but its clinical use is limited by dose-dependent cardiotoxicity. To elucidate the molecular mechanisms underlying DOX-induced cardiomyopathy, we performed quantitative proteomic analysis on DOX-treated human AC-16 cardiomyocytes. The treatment group comprised AC-16 cells exposed to 0.2 µM DOX for 48 hours, with solvent-treated cells serving as the control.

ORGANISM(S): Homo Sapiens

SUBMITTER: Xianwei Wang

PROVIDER: PXD077062 | iProX | Mon Apr 13 00:00:00 BST 2026

REPOSITORIES: iProX

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