A circRNA-encoded protein, circNOP58-466aa, remodels the multiple myeloma microenvironment via liquid-liquid phase separation
Ontology highlight
ABSTRACT: CircNOP58 was significantly upregulated in MM and was associated with inferior survival outcomes. CircNOP58 encodes a previously uncharacterized 466-amino-acid protein, circNOP58-466aa, that undergoes LLPS through intrinsically disordered regions. CircNOP58-466aa promoted MM progression and remodeled the bone marrow tumor microenvironment by enhancing osteoclast differentiation
ORGANISM(S): Homo Sapiens
SUBMITTER:
Pinggang Ding
PROVIDER: PXD079547 | iProX | Wed Jun 10 00:00:00 GMT+01:00 2026
REPOSITORIES: iProX
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