Multi-Stage Native UVPD-MS to Characterize Single Amino Acid Variants of Human Mitochondrial BCAT2

ABSTRACT: We report a multi-stage approach combining collisional activation and 193 nm ultraviolet photodissociation (UVPD) to characterize single amino acid variants of the human mitochondrial enzyme branched-chain amino acid transferase 2 (BCAT2), a protein implicated in chemotherapeutic resistance in glioblastoma tumors.

ORGANISM(S): Homo Sapiens (human)

SUBMITTER: Jennifer S. Brodbelt 

PROVIDER: PXD009447 | JPOST Repository | Thu May 31 00:00:00 BST 2018

REPOSITORIES: jPOST