NGT6

ABSTRACT: Conventional sauna bathing may have some benefits for health such as relaxing, detoxing and promoting metabolism. However, conventional sauna bathing at a high temperature may be harmful for the body to increase a risk for heart failure. Nano-mist sauna has been developed to provide nano-size water particles at a lower temperature. Hence, the nano-mist sauna bathing is expected to be useful for health without risks at high temperature. In this study, we performed a comprehensive proteomics analysis of urine samples obtained from healthy volunteers before and after they had taken sauna bath with nano-mist (n=10) or with conventional mist (n=10) daily for two weeks (4 groups). The average numbers of urine proteins identified by liquid chromatography-linked mass chromatography in each group were from 678 to 753. Interestingly, the protein number was increased after sauna bathing both with nano-mist or with conventional mist. By a quantitative analysis considerable numbers of proteins were obviously up-regulated with more than two-folds in urine samples after the nano-mist sauna bathing. The KEGG pathway analysis showed significant stimulation of lysosome pathway (p= 5.89E-6) after the nano-mist bathing, which may indicate the nano-mist sauna bathing promote metabolism related to the lysosome pathway more efficiently than conventional mist sauna bathing and may be more beneficial for the health.

ORGANISM(S): Homo Sapiens (human)

SUBMITTER: Tadashi Yamamoto 

PROVIDER: PXD013155 | JPOST Repository | Tue Jul 16 00:00:00 BST 2019

REPOSITORIES: jPOST