Proteomics

Dataset Information

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Proteomics of Human and Mouse serum protein


ABSTRACT: Proteomics of human and mouse serum protein using nano-LC-MS/MS. In this study, humanized mice serum were included.

ORGANISM(S): Homo Sapiens (human) Mus Musculus (mouse)

SUBMITTER: Yoshie Kametani 

PROVIDER: PXD021477 | JPOST Repository | Tue Sep 15 00:00:00 BST 2020

REPOSITORIES: jPOST

Dataset's files

Source:
Action DRS
yk-182.raw Raw
yk-184.raw Raw
yk-216.raw Raw
yk-218.raw Raw
yk-238.raw Raw
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Publications

HER2-antigen-specific humoral immune response in breast cancer lymphocytes transplanted in hu-PBL hIL-4 NOG mice.

Ohno Yusuke Y   Ohshima Shino S   Miyamoto Asuka A   Kametani Fuyuki F   Ito Ryoji R   Tsuda Banri B   Kasama Yukie Y   Nakada Shunsuke S   Kashiwagi Hirofumi H   Seki Toshiro T   Yasuda Atsushi A   Ando Kiyoshi K   Ito Mamoru M   Tokuda Yutaka Y   Kametani Yoshie Y  

Scientific reports 20210617 1


The status of humoral immunity of cancer patients is not clear compared to cellular immunity because the ability of specific antibody production is difficult to analyze in vitro. We previously developed a humanized mouse model to evaluate antigen-specific antibody production by transplanting human peripheral blood mononuclear cells (PBMCs) into NOG-hIL-4-Tg mice (hu-PBL hIL-4 NOG). In this study, these mice were transplanted with PBMCs derived from breast cancer patients (BC) and immunized with  ...[more]

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