Chronic high glucose condition reduced expressions of intercellular adhesion molecules and increased intercellular hyperpermeability in periodontal epithelium.

ABSTRACT: There is a close relationship between hyperglycemia in diabetes and progression of periodontal disease. This study aims to investigate the effect of hyperglycemia on the barrier function of gingival epithelial cells as a cause of hyperglycemia-exacerbated periodontitis in diabetes mellitus. Abnormal expressions of adhesion molecules in gingival epithelium in diabetes were compared between db⁄db and control mice.

ORGANISM(S): Mus Musculus (mouse)

SUBMITTER: Yoichiro Kashiwagi 

PROVIDER: PXD035613 | JPOST Repository | Sat Jul 29 00:00:00 BST 2023

REPOSITORIES: jPOST