Proteomic profiling of nuclear fractions of SMARCA4 knockdown samples in HDMB03
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ABSTRACT: SMARCA4 mutations are common in Medulloblastoma but not much is understood about its pathobiology. In this study we prepared SMARCA4 knockdown models using a Group 3 medulloblastoma cell line called HDMB03 and investigated the proteomic changes. Nuclear enrichment was performed using hypertonic and hypotonic buffers. The nuclear enriched fractions were analysed on LC-MS/MS.
ORGANISM(S): Homo Sapiens (human)
SUBMITTER: Prof. Sanjeeva Srivastava
PROVIDER: PXD070641 | JPOST Repository | Wed Mar 25 00:00:00 GMT 2026
REPOSITORIES: jPOST
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